邓明田

性    别

男

学历学位

研究生学历、农学博士学位

职    称

副研究员

导师类别

专业领域

动物遗传育种与繁殖，动物生物工程

研究方向

动物胚胎发育调控

教育与工作经历

2009/09-2013/06 安徽农业大学 动物科学 学士

2013/09-2018/09 澳门新浦新京5197 动物遗传育种与繁殖 农学博士

2018/12--，澳门新浦新京5197 澳门新浦新京5197 团队博士后

联系方式

mtdeng@njau.edu.cn；025-84395381

奖励及荣誉

第十九届中国畜牧兽医学会动物繁殖学分会优秀论文

参加学术团体及任职情况

Biology of Reproduction,  Theriogenology, Frontiers in cell and developmental biology审稿人

承担科研项目

1.   国家自然科学基金委员会，青年科学基金项目，32102546，LncRNA-loc102177005通过RNA结合蛋白YTHDF2调控山羊合子基因组激活的机制研究，2022/01至2024/12，24万元，在研，主持

2.   江苏省基础研究计划（自然科学基金）-青年基金，LncRNA lnc-2217对山羊合子基因组激活的表观遗传调控机制研究，2020/07-2023/06，20万，在研，主持

3.   中国博士后科学基金，Lnc-3712靶向Kdm5b调控山羊核移植胚胎重编程的研究，2019/07-2021/06，8万，在研，主持

4.   国家自然科学基金面上项目，m6A甲基化修饰参与调控山羊体细胞核移植胚胎母源-合子转换期重编程的研究，2020/1-2023/12，59万，在研，参加

5.   国家自然科学基金面上项目，LncRNA通过激活TGFβ/SMAD2信号通路调控湖羊垂体促性腺激素分泌的机制研究，2021/1-2024/12，58万，在研，参加

论文论著：

1.      Mingtian Deng, Baobao  Chen, Yingnan Yang, Yongjie Wan, Zifei Liu, Jun Fu, Feng Wang*,  Characterization of transcriptional activity during ZGA in mammalian SCNT  embryo. Biology of reproduction, 2021, ioab127 (IF=4.285)

2.      Mingtian Deng#,  Yongjie Wan#, Zifei Liu, Cai Yu, Baobao Chen, Yanli Zhang*, Feng Wang*, Long  non-coding RNA lnc_3712 impedes nuclear reprogramming via repressing Kdm5b, Molecular  Therapy-Nucleic Acids, 2021,24:54-66（IF=8.886, top10）

3.      Yu Cai#, Mingtian Deng#, Qifan Zhang,  Zifei Liu, Liang Wang, Wenwen Sheng, Yanli Zhang, Peihua You, Ziyu Wang*, Feng  Wang*. Effects of dietary betaine supplementation on biochemical parameters  of blood and testicular oxidative stress in Hu sheep. Theriogenology,  2021, 164: 65-73（IF=2.740, top20）

4.      Mingtian Deng,  Baobao Chen, Yongjie Wan, Zifei Liu, Yu Cai, Guoming Zhang, Yixuan Fan, Yanli  Zhang* and Feng Wang*, YTHDF2 Regulates Maternal Transcriptome Degradation  and Embryo Development in Goat. Frontiers in Cell and Developmental  Biology, 2020, 8: 1040-1050（IF=6.684, top20）

5.      Mingtian Deng, Baobao  Chen, Zifei Liu, Yongjie Wan, Hua Yang, Yu Cai, Jianguo Zhou, Yanli Zhang, Feng  Wang*. Aberrant DNA and histone methylation during zygotic genome activation  in goat cloned embryos. Theriogenology,  2020, 148: 27-36（IF=2.740，top20）

6.      Mingtian Deng,  Guomin Zhang, Yu Cai, Zifei Liu, Yanli Zhang, Fanxing Meng, Feng Wang,  Yongjie Wan*, DNA methylation dynamics during zygotic genome activation in  goat. Theriogenology, 2020, 156: 144-154（IF=2.740，top20）

7.      Mingtian Deng,  Zifei Liu, BaoBao Chen, Yu Cai, Yongjie Wan*, Feng Wang*. Locus-Specific Regulation of  Xist Expression Using the CRISPR-Cas9-Based System. DNA Cell Biol, 2020, 39(4): 572-578（IF=3.311）

8.      Mingtian Deng,  Baobao Chen, Zifei Liu, Yu Cai, Yongjie Wan, Jianguo Zhou, Feng Wang*. Exchanges of histone methylation  and variants during mouse zygotic genome activation. Zygote, 2020, 28(1): 51-58

9.      邓明田, 王锋 (2020). 哺乳动物合子基因组激活调控的研究进展. 黑龙江动物繁殖 28: 37-41.

10.   Mingtian Deng,  Zifei Liu, Caifang Ren, Shiyu An, Yongjie Wan*, Feng Wang*. Highly methylated Xist in SCNT embryos was  retained in deceased cloned female goats. Reproduction, Fertility and  Development, 2019, 31(5): 855-866

11.   Mingtian Deng,  Zifei Liu, Caifang Ren, Guomin Zhang, Jing Pang, Yanli Zhang, Feng Wang*,  Yongjie Wan*. Long noncoding RNAs exchange during zygotic genome activation  in goat. Biology of reproduction,  2018, 99(4): 707-717（IF= 4.285）

12.   Mingtian Deng,  Caifang Ren, Zifei Liu, Guomin Zhang, Feng Wang*, Yongjie Wan*. Epigenetic status of H19-Igf2  imprinted genes and loss of 5-hydroxymethylcytosine in the brain of cloned  goats. Cellular reprogramming, 2017, 19(3): 199-207

13.   Yongjie Wan^#, Mingtian  Deng^#, Guomin Zhang, Caifang Ren, Hao Zhang, Yanli Zhang,  Lizhong Wang, Feng Wang*. Abnormal  expression of DNA methyltransferases and genomic imprinting in cloned goat  fibroblasts. Cell biology international, 2016, 40(1): 74-82